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王开金

来源:生命科学学院  发布时间:2017-03-27 访问次数:12261


    • 姓    名:王开金

      邮箱:wkjahla@163.com

      职称:教授

      联系电话:13695698475                 

      地址:安徽省合肥市经济技术开发区九龙路111号,安徽大学生命科学学院 

      邮政编码:230601

      科学领域描述:

      主要以区域特色药用资源植物为研究对象,利用植物化学技术手段,开展天然活性成分的提取、分离、结构鉴定与修饰改造、以及生物活性研究,进行药用资源植物活性部位物质基础及成药性相关研发工作。

      主要成员:

      姜杰

      主要研究方向:

      天然产(药)物化学;资源植物学

      研究项目:

      桑黄抗肿瘤化学物质基础研究与应用开发(企业合作项目)

      玉米须降糖护肾活性物质与功能产品的开发(2016振兴计划项目)

      主要发表文章:

      Wei Ma, Kai-Jin Wang, Chen-Shu Cheng, Guo-qing Yan, Wei-Li Lu, Jing-Fang Ge, Yong-Xian Cheng, Ning Li. Bioactive Compounds from Cornus officinalis Fruits and Their Effects on Diabetic Nephropathy. Journal of Ethnopharmacology, 2014, 153: 840-845. 

      Lei Di, Guo-Qing Yan, Ling-Yu Wang, Wei Ma, Kai-Jin Wang, Ning Li. Two New Neolignans from Patrinia scabra with Potent Cytotoxic Activity against HeLa and MNK-45 Cells. Archives of Pharmacal Research, 2013, 36: 1198-1203.

      Ning Li, Lei Di, Wen-Chao Gao, Kai-Jin Wang, Ling-Bo Zu. Cytotoxic iridoids from the roots of Patrinia scabra. Journal of Natural Products, 2012, 75: 1723-1728.

      Zhi Wang, Kai-Jin Wang, Chen-Shu Cheng, Ning Li, Tian-Ming Wang, Lei Di.  Gingerol Derivatives from the Rhizomes of Zingiber Officinale. Zeitschrift für Naturforschung B. 2011, 66: 740-744.

      Kai-Jin Wang, Cui-Cui Zhu, Lei Di, Ning Li, You-Xing Zhao. New Norlignan derivatives from Curculigo capitulata. Fitoterapia, 2010, 81:869-872.

      唐俊,李宁,戴好富,王开金. 草豆蔻种子化学成分及其NF-κB激活抑制作用与抗肿瘤活性. 中国中药杂志,2010, 35: 1710-1714.

      Ning Li, Tian-Ming Wang, Kai-Jin Wang, You-Xing Zhao. Norlignans from Rhizomes of Curculigo sinensis. Helvetica Chimica Acta, 2010, 93: 724-728.

      Cui-Cui Zhu, Tian-Ming Wang, Kai-Jin Wang, Ning Li. A New Chlorine- containing Glucosyl-fused compound from Curculigo glabrescens. Zeitschrift für Naturforschung B. 2009, 64: 1077-1080

      Kai-jin Wang, Ning Li, Hu Wang. New Acetylenic Norlignan Compounds from Rhizomes of Curculigo crassifolia. Molecules, 2008, 13: 1696-1701.

      Kai-Jin Wang, Chong-Ren Yang, Ying-Jun Zhang. Phenolic antioxidants from Chinese toon (fresh young leaves and shoots of Toona sinensis). Food Chemistry, 2007, 101: 365-371.

      Kai-Jin Wang, Ying-Jun Zhang, Chong-Ren Yang. New Phenolic Constituents from Balanophora polyandro with Radical-Scavenging Activity. Chemistry & Biodiversity, 2006, 3: 1317-1324. 

      Ning Li, Kai-jin Wang, Ji-Jun Chen, Jun Zhou. Two novel glucosyl-fused compounds from Curculigo crassifolia (Hypoxidaceae). Tetrahedron Letters, 2005, 46: 6445-6447.

      Kai-Jin Wang, Ying-Jun Zhang, Chong-Ren Yang. Antioxidant phenolic constituents from Fagopyrum dibotrys. Journal of Ethnopharmacology, 2005, 99: 259-264.