您现在的位置:首页  师资队伍

吴庆喜

来源:生命科学学院  发布时间:2017-03-17 访问次数:10002

  • 姓名:吴庆喜

    单位:安徽大学 生命科学学院

    职称:副教授

    邮箱wuqx@ahu.edu.cn

    地址:安徽省合肥市经开区九龙路111号安徽大学磬苑校区理工C楼,230601

    个人简介:

      吴庆喜,男,副教授,硕士生导师,浙江大学工学博士、博士后,加拿大The University of Western Ontario访问学者。从事食品与生物化工、生物工程、生物材料、生物制药等交叉学科领域的教学和科研工作,聚焦生物医药材料与活性物质高附加值利用应用基础研究。主持国家自然科学基金、安徽省重点研究与开发计划及安徽省自然科学基金等科研项目,参与国家自然科学基金面上项目(排名第二)。青年教师骨干,入选安徽大学首批“优秀人才计划”。作为第一作者/通讯作者发表论文24篇:Food ChemCellulose (Front Cover)Front Chem Sci EngInt J PharmMat Sci Eng C、《高分子材料科学与工程》、《微生物学报》等期刊上,中科院一区/二区17篇(Top 12篇),被引用400余次;申请发明专利10项,授权5项。现为中国化工学会、中国生物工程学会等会员,LangmuirCelluloseCarbohyd Polym、《高分子通报》等期刊审稿人,完成审稿26篇。

    研究方向:食品与生物化工应用基础研究

    # 生物医药材料:缓释控释递送载体、纳米靶向及生物降解医药材料开发

    # 生物活性物质:真菌多糖功效活性、肠道微生态调控及苦胆高附加值利用

    # 应用微生物学:真菌菌丝体功能化、功能微生物发掘及微纳载体固定化应用

    科研项目:主持

    # 国家自然科学青年基金:酶触型缓释PEC微载体自组装及其复层结构与给药性能间效应机制研究

    # 安徽省重点研究与开发计划项目:动物苦胆资源的微生物全细胞催化转化技术研发与高效利用

    # 安徽省自然科学青年基金:食用菌茅草菇多糖的结构及其抗肿瘤活性研究

    # 安徽省高校自然科学研究重点项目:茅草菇多糖-硒纳米粒复合物的肿瘤细胞生长抑制作用及协同增效机制研究

    # 中国博士后科学基金:靶向性多糖类药物微载体的自组装及其给药行为研究

    # 国家重点实验室开放基金:瓜片多糖抗衰老活性及调控肠道菌群发育作用机制

    发表文章:第一作者/通讯作者*

    # Zhi Wu, Dong Wang, Cai-Xia Liu, Xiao-Hui Wang, Yan Chen, Qing-Xi Wu*, Jin-Song Zhang*, Macrophage immunity promotion effect of polysaccharide LGP-1 from Guapian tea viaPI3K/AKT and NF-κB signaling pathway. Journal of Functional Foods, 2022, 89, 104946. (2)

    # Xiao-Hui Wang, Xiao-Du Cheng, Dong Wang, Zhi Wu, Qing-Xi Wu*, Yan Chen, Antioxidant and anti-aging effects of polysaccharide LDP-1 from wild Lactarius deliciosus on Caenorhabditis elegans. Food & Nutrition Research, 2022, 62, 8110. (2)

    # Ling Tang, Yi-Hong Chen, Qiong Wang, Xiao-Hui Wang, Qing-Xi Wu*, Zhi-Feng Ding, Microencapsulation of functional Ovalbumin and Bovine serum albumin with Polylysine-Alginate complex for sustained protein vehicle’s development. Food Chemistry, 2022, 368, 130902. (1区,Top)

    # Jin Zhao, Qing-Xi Wu*, Xiao-Du Cheng, Ting Su, Xiao-Hui Wang, Wen-Na Zhang, Yong-Ming Lu, Yan Chen*, Biodegradation and detoxification of the triphenylmethane dye coomassie brilliant blue by the extracellular enzymes from mycelia of Lactarius deliciosus. Frontiers of Chemical Science and Engineering, 2021, 15(2): 421-436. (2)

    # Xiao-Hui Wang, Ting Su, Jin Zhao, Zhi Wu, Dong Wang, Wen-Na Zhang, Qing-Xi Wu*, Yan Chen, Fabrication of polysaccharides-based hydrogel films for transdermal sustained delivery of Ibuprofen.Cellulose, 2020, 27: 10277-10292. (1区,Top)

    # Qing-Xi Wu#*, Zi-Dan Wang#, Meng-Fei Zheng, Ting Su, Xiao-Hui Wang, Yi-Xin Guan, Yan Chen, Development of metformin hydrochloride loaded dissolving tablets with novel carboxymethylcellulose/poly-L-lysine/TPP complex. International Journal of Biological Macromolecules, 2020, 155: 411-420. (2)

    # Xiao-Du Cheng, Qing-Xi Wu*, Jin Zhao, Ting Su, Yong-Ming Lu, Wen-Na Zhang, Ya Wang, Yan Chen*, Immunomodulatory effect of a polysaccharide fraction on RAW 264.7 macrophages extracted from the wild Lactariusdeliciosus. International Journal of Biological Macromolecules, 2019,128: 732-739. (2)

    # Ting Su, Qing-Xi Wu*, Yan Chen, Jin Zhao, Xiao-Du Cheng, Juan Chen, Fabrication of the polyphosphates patched cellulose sulfate-chitosan hydrochloride microcapsules and as vehicles for sustained drug release. International Journal of Pharmaceutics, 2019, 555: 291-302. (2区,Top)

    # Qing-Xi Wu, Yi-Xin Guan, Shan-Jing Yao*, Sodium cellulose sulfate: a promising biomaterial used for microcarriers’ designing. Frontiers of Chemical Science and Engineering, 2019, 13(1): 46-58. (2)

    # Qing-Xi Wu*, Jun-Qi Yu, Wei Ying, Ting Su, Xiao-Du Cheng, Jin Zhao, Yan Chen*, Cultivation of the wild Ganoderma gibbosum mycelia via the submerged liquid fermentation for inter/extra-cellular polysaccharides. International Journal of Agriculture and Biology, 2018, 20(5): 1218-1224. (4)

    # Qing-Xi Wu*#, Dan-Dan Wang#, Ting Su, Xiao-Du Cheng, Xin Xu, Yan Chen*, Self-assembly of polyelectrolyte complexes microcapsules with natural polysaccharides for sustained drug release. Cellulose, 2017, 24: 4949-4962. (1区,Top)

    # Qing-Xi Wu, Xin Xu, Qiu Xie, Wang-Yu Tong*, Yan Chen, Evaluation of chitosan hydrochloride-alginate microcapsules as an enteric micro-probiotic-carrier with dual protective barriers. International Journal of Biological Macromolecules, 2016,93: 665-671. (2)

    # Qing-Xi Wu, Xin Xu, Zu-Li Wang, Shan-Jing Yao*, Wang-Yu Tong, Yan Chen, Effect of the cross-linking agent on formations and performances of NaCS-CS/WSC microcapsules. Colloids and Surfaces B-Biointerfaces, 2016,147: 416-421. (2)

    # Qing-Xi Wu, Dong-Qiang Lin, Shan-Jing Yao*, Fabrication and formation studies on single-walled CA/NaCS-WSC microcapsules. Materials Science & Engineering C-Materials for Biological Applications, 2016, 59: 909-915. (2)

    # Qing-Xi Wu, Dong-Qiang Lin, Shan-Jing Yao*, Design of chitosan and its water soluble derivatives-based drug carriers with polyelectrolyte complexes. Marine Drugs, 2014, 12(12): 6236-6253. (2)

    # Qing-Xi Wu, Mu-Zhen Li, Shan-Jing Yao*, Performances of NaCS-WSC protein drug microcapsules with different degree of substitution of NaCS using sodium polyphosphate as cross-linking agent. Cellulose, 2014, 21(3): 1897-1908. (Front Cover) (1区,Top)

    # Qing-Xi Wu, Qi-Lei Zhang, Dong-Qiang Lin, Shan-Jing Yao*, Characterization of novel lactoferrin loaded capsules prepared with polyelectrolyte complexes. International Journal of Pharmaceutics, 2013, 455(1-2): 124-131. (2区,Top)

    # Qing-Xi Wu, Shan-Jing Yao*, Novel NaCS-CS-PPS microcapsules as a potential enzyme-triggered release carrier for highly-loading 5-ASA. Colloids and Surfaces B-Biointerfaces, 2013, 109: 147-153. (2)

    # 赵锦,王晓慧,王栋吴志吴庆喜*陈彦,茅草菇菌丝球对铬黑T的脱色降解性能及毒性评价,微生物学报202262(1)1-11.

    # 王栋苏婷吴庆喜*PEC载药微胶囊的自组装及其缓释性能高分子材料科学与工程EI202137(8)25-32.

    # 吴庆喜,姚善泾*,口服结肠靶向给药系统和制备方法的研究进展,化工学报EI201364(1)210-222.

    # 吴庆喜,姚善泾*,新型负载5-氨基水杨酸微胶囊的制备及其载药效果,过程工程学报201313(1)117-123.

    # 吴庆喜,程凯*,杨季芳*,陈吉刚,赵以军,许敏,一株海洋牟勒氏角毛藻(Chaetoceros muelleri)病毒的分离与初步鉴定,海洋与湖沼201142(3)455-459.

    # 吴庆喜,程凯,许丽娜,王媛媛,赵以军,许敏*1株新型小球藻病毒的分离,华中师范大学学报(自然科学版)201044(1)105-108.

    授权发明专利:第一发明人

    #一种具有高存活率的耐胃酸型地衣芽孢杆菌微胶囊的制备方法,ZL201510387820.5

    #一种具有多层核壳结构的缓释载药微胶囊的制备方法,ZL201710514209.3

    # 一种具有高效去除染料功能的野生茅草菇菌丝体的制备方法及其用途, ZL201810794425.2

    # 一种具有肿瘤细胞生长抑制效应的茅草菇多糖-硒纳米粒复合物及其制备与用途,ZL202011015978.7

    # 种植物蛋白-熊去氧胆酸缓释纳米粒复合微囊及其制备方法,ZL 202011146484.